What People Are Saying

Pat's shocking story raises so many important questions about the quality and process of "informed" consent in phase I trials and the need for the oncology community to stop using obscure language like "safety test" and talk more openly and honestly about organ toxicity as a real life side effect. Thank you Pat for all the work you've done on this issue.

Mary K
Thursday, March 2, 2017

I just wanted to let you know that I finished reading your book "Lethal Dose" this afternoon. I borrowed it from the Vancouver Public Library (Inter Library Loan) as there was not a copy here in Sechelt. Pat, what an eye opener to me regarding Phase 1 Drug Trials and all that ensued. I am so sorry that you and your husband Dave had to go through this horrendous experience. I don't know how you stayed so strong throughout - I doubt I could have. And to fight for changes after Dave's passing - that must have taken so much energy and passion. I admire your courage. Thanks for sharing your story!

Sunday, June 24, 2012

'Lethal Dose' is a testament to those who spend their last days trying to make the world a better place for complete strangers faced with the challenges of a life-threatening disease and to the families who support them.

The story of Dave and Pat is a heart-wrenching eye-opener into the world of clinical research. I recommend it as essential reading for anyone who is considering participation in a Phase 1 drug trial, including physicians and nurses, and for every donor whose financial gift may be directed towards drug research.

Pat, thank you for sharing the story. Thank you for your advocacy in setting up the foundation "Research with Respect" and for your efforts to effect much-needed change.

Saturday, April 28, 2012

Thank you Pat for writing this book; it is a wonderful tribute to Dave, and it sends an important message to us all.We know that it is necessary to be proactive during all phases of our lives, but as your book points out, we need to be especially so as our death approaches. The medical community needs volunteers for trials, but the brave persons who submit to the experimental treatments and procedures need to be fully aware of what they are going to be asked to do.I have a friend who had throat cancer. At her doctors' urging, she underwent surgery that removed her tongue along with the tumor. Sara could no longer eat or talk - the two things she loved most in life.Sara lived for another year after that operation, but the tumor returned. When she did pass away, her son questioned the doctors having recommended such radical intervention. He replied, "Well, we gave her another year of life." "Yes, but what kind of life?" answered her son.I hope that "Lethal Dose" will find its way into the hands of every family that finds itself facing these difficult choices.With love,

Saturday, April 21, 2012

I read Lethal Dose over a weekend. The book is emotionally intense, filled with descriptive details and dialogues.I am amazed by the trials and tribulations that Dave went through during his past few weeks and days of his life in volunteering his body and remaining time for betterment of cancer patients and society.The introduction of the book mentions that you had to keep descriptive adjectives to a minimum at the guidance of your lawyer. In spite of this, I could sense your strong passion on this personal matter.You have clearly demonstrated your energy and enthusiasm to not only shed light on phase 1 cancer clinical trial to the readers, but also your dedication in your advocacy nonprofit organization. Thank you for sharing your story with me.

Brian C
Sunday, February 26, 2012

Thank you for sharing your story. As a nurse, that has never been in that part of healthcare, it certainly is an eye opener to how the trials can be handled. My heart goes out to you and your family, God Bless

KD Elliott
Sunday, January 22, 2012

Thank you Pat for bringing this void in Canada's medical laws to my attention. You are a very astute speaker and an inspirational writer. I have sent my own letter off to Health Canada and hopefully soon some positive changes will come about ! You are a very motivated person in this quest and I wish you much sucess. I was talking with Val, my neighbour, and she holds you in high regards as well, you are a blessed lady. Thank You ,


Thursday, January 12, 2012

Dear Pat,Thankyou for taking the effort to record both the wonderful memories of the life that you and Dave shared, and the horrific times you shared from the time of Dave's cancer diagnosis until his death. The trials you went through during the Phase 1 cancer clinical trial were unimaginable and could certainly have been made easier with proper support and care.Through my reading of the earlier part of your book, I feel I know you and Dave a lot better, and for that I am grateful. My knowledge of clinical research trials in any phase was sadly lacking, and in this aspect you have given me an education.I think that your book would be a very valuable resource book for anyone considering volunteering their bodies for cancer research, and I'm glad you have sent it out to public libraries.I'd like to take this opportunity to say how thankful I am for Dave's huge contribution to society. I'm not sure I could be so brave under the circumstances, and especially knowing what I now know.Pat, I'd like to thank you as well for both your support of Dave during the cancer research trials, and for the positive changes you have been making to benefit present and future cancer trial volunteers. What you have accomplished is amazing!

Monday, January 2, 2012

Dear Pat -I thought I had reached the point of crying less at the death of my dear husband Bob last January; Then it all resumed on reading "Lethal Dose" I felt elated at your vivid account of your and David's wonderful life together and then extreme sadness and anger at the unfeeling incompetence leading to David's death. I admire your courage, Pat, at bringing this to light. 

Pauline Mills
Friday, December 30, 2011

I read Lethal Dose in one sitting. Every Canadian, and anyone who wants to learn more about cancer research should read this eye-opening book.

The lack of even basic support and medical care you and your husband received as you struggled through the disastrous last few days of Dave's life is horrifying and unacceptable.

A person who donates their deceased body to science is to be commended.  As your sister Jackie suggests, a person who donates their *living* body to science is giving a priceless gift to humankind and should be treated with the utmost care and respect. 

Thank you for everything you are doing, Pat. I have handed out several copies of your book and my letter is ready to be mailed once I return to Canada.

Donna Derrien
Saturday, November 26, 2011